Developing Deep and Comprehensive Portfolio of NCEs and Other Innovative Solutions

Our robust pipeline features novel chemical entities (NCEs) with strong intellectual property protection, targeting critical unmet medical needs in addiction treatment and beyond.

Presentation slide developing deep and comprehensive portfolio of NCEs and Other Innovative Solutions

Issued Patent Protection into the mid 2040s Anchored by Composition-of-Matter Patents

SOPH-110S

  • Composition of Matter is covered by U.S. Patent No. 11,649,208, which expires November 30, 2041, subject to patent term extension
  • Foreign applications pending in Australia, Canada, China, Eurasia (Russia), Europe, Israel, India, Japan, South Korea, and New Zealand
  • Co-crystal Form is covered by U.S. Patent No. 12,171,753, which expires June 28, 2042
  • Foreign applications pending in China, Europe, and Japan

DETC-MeSO

  • Covered by U.S. Patent No. 11,746,089, which expires November 30, 2041, subject to patent term extension
  • Foreign applications pending in Australia, Canada, China, Eurasia (Russia), Europe, Israel, India, Japan, South Korea, and New Zealand
  • Co-crystal Form is covered by U.S. Patent No. 12,171,753, which expires June 28, 2042
  • Foreign applications pending in China, Europe, and Japan
  • Provisional application pending related to conjugates of DETC-MeSO analogs with anti-abuse agents
  • Fillings in process for SOPH123 by end of year
  • Additional filings planned for new indications, pharmaceutical formulations, PK/PD profiles, etc.

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